Description

2-(Propylthio)Pyridine-3-Carbonyl Chloride is a versatile and reactive organosulfur building block used in advanced organic synthesis. Its core value lies in its bifunctional nature, combining a reactive acid chloride group with a pyridine-thioether moiety, enabling the construction of complex heterocyclic scaffolds. This intermediate is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of functionalized polymers and organic electronic materials with tailored properties.
• Custom Synthesis and R&D: A critical reagent for contract research organizations (CROs) and academic labs exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-(Propylthio)Pyridine-3-Carbonyl Chloride
CAS No.	175135-24-7
Molecular Formula	C9H10ClNOS
Molecular Weight	215.70 g/mol
Synonyms	3-Pyridinecarbonyl chloride, 2-(propylthio)-; 2-(Propylsulfanyl)nicotinoyl chloride; 2-(Propylthio)nicotinoyl chloride; 2-(n-Propylthio)pyridine-3-carbonyl chloride; 2-Propylthiopyridine-3-carbonyl chloride; Nicotinoyl chloride, 2-(propylthio)-; 175135-24-7
EINECS	Contact for details

Quality Control

Every batch of 2-(Propylthio)Pyridine-3-Carbonyl Chloride is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure consistency and purity for your critical synthesis steps. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and IR are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Light yellow to yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.