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2-(6-Amino-9H-Purin-9-Yl)-1,4-Anhydro-2-Deoxy-L-Arabinitol CAS NO 174955-57-8


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CAS No.:174955-57-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(6-Amino-9H-Purin-9-Yl)-1,4-Anhydro-2-Deoxy-L-Arabinitol is a high-purity nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound is critical for the synthesis of novel antiviral and anticancer agents, offering researchers a precise tool for probing biological mechanisms and developing targeted therapies. It is essential for biotechnology and pharmaceutical companies engaged in the discovery of next-generation nucleotide-based therapeutics.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and DNA/RNA synthesis.
  • Pro-drug Development: Serves as a core structure for designing pro-drugs with improved bioavailability and targeted delivery.
  • Antiviral Agent Synthesis: Integral to the research and development pipeline for new treatments against viral infections.
  • Molecular Biology: Employed in the study of polymerase activity and the mechanism of action of nucleoside-based drugs.
  • Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in QC laboratories.

Basic Information

Product Name 2-(6-Amino-9H-Purin-9-Yl)-1,4-Anhydro-2-Deoxy-L-Arabinitol
CAS No. 174955-57-8
Molecular Formula C11H13N5O3
Molecular Weight 263.25 g/mol
Synonyms L-Arabinitol, 2-(6-amino-9H-purin-9-yl)-1,4-anhydro-2-deoxy-; 9-(1,4-Anhydro-2-deoxy-β-L-arabinitol-2-yl)adenine; 2'-Deoxy-2'-fluoro-β-L-arabinofuranosyladenine impurity; L-FMA; 2-Fluoro-L-arabinofuranosyladenine related compound; β-L-2'-Fluoro-2'-deoxyarabinofuranosyladenine; 2'-F-β-L-araA; L-F-ara-Adenine
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Quality Control

Our 2-(6-Amino-9H-Purin-9-Yl)-1,4-Anhydro-2-Deoxy-L-Arabinitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Related Substances (HPLC) Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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