Description

(1S,2R)-2-(Azidomethyl)-N,n-Diethyl-1-Phenylcyclopropanecarboxamide CAS NO 174848-98-7 is a high-purity, stereochemically defined cyclopropane derivative featuring an azidomethyl functional group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, including protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a constrained scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Click Chemistry: The azide group enables efficient, high-yielding copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and polymer functionalization.
• Chemical Biology Probes: Acts as a building block for creating activity-based probes and molecular tags for studying biological systems.
• Agrochemical Synthesis: Potential intermediate in the development of novel pesticides and herbicides with enhanced activity.
• Material Science: Used in the synthesis of specialty polymers and functional materials with tailored properties.

Basic Information

Item	Detail
Product Name	(1S,2R)-2-(Azidomethyl)-N,n-Diethyl-1-Phenylcyclopropanecarboxamide
CAS No.	174848-98-7
Molecular Formula	C16H22N4O
Molecular Weight	286.38 g/mol
Synonyms	(1S,2R)-2-(Azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide; N,N-Diethyl-2-(azidomethyl)-1-phenylcyclopropanecarboxamide, (1S,2R)-; (1S,2R)-2-(Azidomethyl)-1-phenyl-N,N-diethylcyclopropanecarboxamide; Cyclopropanecarboxamide, 2-(azidomethyl)-N,N-diethyl-1-phenyl-, (1S,2R)-; 174848-98-7; Azidomethyl Cyclopropane Carboxamide Derivative; trans-2-(Azidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our (1S,2R)-2-(Azidomethyl)-N,n-Diethyl-1-Phenylcyclopropanecarboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.