Description

Tavaborole CAS NO 174671-46-6 is a potent, small-molecule antifungal agent belonging to the oxaborole class. Its primary value lies in its unique mechanism of action, selectively inhibiting fungal protein synthesis, which makes it highly effective against onychomycosis (fungal nail infections). This compound is essential for pharmaceutical manufacturers and research institutions developing topical antifungal treatments. Its targeted activity and favorable safety profile have established it as a key active pharmaceutical ingredient (API) in dermatological therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in topical antifungal solutions, creams, and gels for the treatment of onychomycosis.
• Dermatological Research: A critical reference standard and tool compound for studying fungal pathogenesis and screening novel antifungal agents.
• Drug Formulation Development: Used in pre-formulation and formulation studies for optimizing drug delivery, stability, and efficacy in topical products.
• Quality Control & Analytical Testing: Serves as a certified reference material (CRM) for HPLC, LC-MS, and NMR method development and validation in QC laboratories.
• Clinical Trial Material (CTM): Supplied as a high-purity intermediate or finished API for use in Phase I-IV clinical studies.
• Veterinary Medicine: Potential application in developing antifungal treatments for animal health.

Basic Information

Product Name	Tavaborole
CAS No.	174671-46-6
Molecular Formula	C7H6BFO2
Molecular Weight	151.93 g/mol
Synonyms	5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole; AN2690; AN-2690; AN 2690; Kerydin (Brand Name); 5-Fluoro-1-hydroxy-1,3-dihydro-2,1-benzoxaborole; 1-Hydroxy-5-fluoro-1,3-dihydro-2,1-benzoxaborole
EINECS	Contact for details

Quality Control

Our Tavaborole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical development. We provide full traceability and detailed Certificates of Analysis (COA) that include data for identity, purity, and specified impurities. Our quality commitment aligns with ICH guidelines and current Good Manufacturing Practice (cGMP) principles for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.