Description

Edotecarin is a synthetic, small-molecule compound belonging to the class of indolocarbazole topoisomerase I inhibitors. This product is of significant interest for advanced pharmaceutical research and development due to its potent biological activity. It is primarily utilized by researchers and developers in the oncology and life sciences sectors for preclinical studies and as a reference standard.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug substance and product testing.
• Oncology Research: Serves as a key investigational agent in preclinical studies to evaluate antitumor efficacy and mechanism of action.
• Biochemical Assays: Employed in enzymatic assays to study topoisomerase I inhibition and related cellular pathways.
• Drug Discovery & Development: Acts as a lead compound or benchmark in the discovery and optimization of novel chemotherapeutic agents.
• Academic Research: Utilized in university and institutional laboratories for fundamental cancer biology and pharmacology studies.

Basic Information

Product Name	Edotecarin
CAS No.	174402-32-5
Molecular Formula	C30H30N4O6
Molecular Weight	542.58 g/mol
Synonyms	J-107088; J 107088; J107088; Edotecarin hydrate; (+)-Edotecarin; (1S,3aR,14bS)-10-Methoxy-1,2,3,3a,4,5,13,14b-octahydro-3a,14b-(epiminomethano)-3H,13H-indolo[2',3':3,4]pyrido[2,1-b][1,3]oxazine-1,13-dione hydrate; NSC 722427; Topoisomerase I inhibitor J-107088
EINECS	Contact for details

Quality Control

Our Edotecarin is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We support compliance with cGMP standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storage at 2-8°C is recommended.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.