Description

Diphenyl Pyrrolidine-2-Phosphonate Hcl is a high-purity, specialized organophosphorus compound used as a key intermediate in advanced chemical synthesis. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for innovative synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Research: Used in the development of peptidomimetics and protease inhibitors due to its pyrrolidine-phosphonate scaffold.
• Ligand and Catalyst Precursor: Serves as a precursor for chiral phosphine ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: Employed in the research and production of advanced herbicides and plant growth regulators.
• Material Science: Investigated for the development of specialized polymers and functional materials with unique properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Diphenyl Pyrrolidine-2-Phosphonate Hcl
CAS No.	174298-14-7
Molecular Formula	C₁₆H₁₉ClNO₃P
Molecular Weight	339.75 g/mol
Synonyms	Diphenyl (pyrrolidin-2-yl)phosphonate hydrochloride; 2-Pyrrolidinylphosphonic Acid Diphenyl Ester Hydrochloride; Pyrrolidine-2-phosphonic Acid Diphenyl Ester Hydrochloride; (2-Pyrrolidinyl)phosphonic Acid Diphenyl Ester HCl; NSC 405122; 1-(Diphenoxyphosphoryl)pyrrolidine Hydrochloride; (R/S)-Diphenyl Pyrrolidine-2-phosphonate Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Diphenyl Pyrrolidine-2-Phosphonate Hcl is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.