Description

Voriconazole Vfend is a potent, broad-spectrum triazole antifungal agent used to treat serious systemic fungal infections. Its primary value lies in its efficacy against invasive aspergillosis and other life-threatening mycoses, including those resistant to other azole antifungals. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing generic injectable, oral, and ophthalmic formulations targeting immunocompromised patients in hospital and clinical settings.

Application

• Pharmaceutical API: Core ingredient for the manufacture of generic antifungal medications under the brand name Vfend®.
• Injectable Formulations: Production of lyophilized powders for intravenous (IV) infusion to treat invasive aspergillosis, candidemia, and other serious fungal infections.
• Oral Solid Dosage Forms: Formulation into tablets for continuation therapy and treatment of esophageal candidiasis.
• Ophthalmic Preparations: Used in developing treatments for fungal keratitis and other ocular fungal infections.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological studies and the development of novel antifungal agents.
• Veterinary Pharmaceuticals: Investigational use in developing antifungal treatments for serious fungal infections in animals.

Basic Information

Product Name	Voriconazole Vfend
CAS No.	173967-54-9
Molecular Formula	C16H14F3N5O
Molecular Weight	349.31 g/mol
Synonyms	Voriconazole; UK-109,496; (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; Vfend; Vorizol; Vfend® Brand Voriconazole; Antifungal Agent UK-109496
EINECS	Contact for details

Quality Control

Our Voriconazole API is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical use, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) is provided for every shipment, detailing results for identity, purity, assay, and impurity profiles. We support compliance with cGMP, ICH Q7, and relevant regulatory requirements for global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.