Description

1H-Pyrazole-5-Carbonyl Chloride, 3-Chloro-1-Methyl- (9Ci) is a high-value, reactive organic intermediate characterized by its acid chloride functional group. This compound matters for its role as a key building block in the synthesis of more complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the creation of specialized polymers, ligands for catalysis, and advanced organic materials.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling biomolecules or creating activity-based probes for enzyme studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1H-Pyrazole-5-Carbonyl Chloride, 3-Chloro-1-Methyl- (9Ci)
CAS No.	173841-83-3
Molecular Formula	C5H4Cl2N2O
Molecular Weight	178.99 g/mol
Synonyms	3-Chloro-1-methyl-1H-pyrazole-5-carbonyl chloride; 3-Chloro-1-methylpyrazole-5-carbonyl chloride; 1-Methyl-3-chloro-1H-pyrazole-5-carbonyl chloride; 5-Chlorocarbonyl-3-chloro-1-methylpyrazole; 3-Chloro-1-methyl-1H-pyrazole-5-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-5-Carbonyl Chloride, 3-Chloro-1-Methyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned procedures guarantees a reliable supply of this high-purity intermediate for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.