Description

Benzyl 2-Azidoacetate is a versatile organic building block featuring both an azido group and a benzyl-protected carboxylic acid. This bifunctional nature makes it a critical intermediate in the synthesis of complex molecules, particularly through click chemistry and peptide coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, materials science, and the development of novel bioconjugates.

Application

• Click Chemistry Reagent: Serves as a key precursor for Huisgen 1,3-dipolar cycloaddition reactions, enabling the efficient synthesis of 1,2,3-triazoles for drug discovery and polymer science.
• Peptide Synthesis Intermediate: Used in the preparation of azido-functionalized amino acids and peptides, facilitating site-specific modifications and labeling.
• Bioconjugation Linker: Enables the covalent attachment of biomolecules (e.g., proteins, antibodies) to drugs, dyes, or solid surfaces for diagnostic and therapeutic applications.
• Polymer Functionalization: Incorporates azide functionality into polymer backbones or side chains for creating advanced materials with tailored properties.
• Chemical Biology Probes: Acts as a building block for synthesizing activity-based probes to study enzyme function and metabolic pathways.
• Agrochemical Intermediate: Employed in the research and development of novel active ingredients with specific biological activity.

Basic Information

Product Name	Benzyl 2-Azidoacetate
CAS No.	173601-46-2
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	2-Azidoacetic Acid Benzyl Ester; Benzyl Azidoacetate; Azidoacetic Acid Benzyl Ester; N3CH2COOCH2C6H5; (Azidoacetoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our Benzyl 2-Azidoacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled with appropriate precautions to minimize exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.