Description

2'--C-Methyl-6-Azauridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and a key intermediate in the synthesis of novel antiviral and anticancer therapeutics. It is primarily sought after by research institutions, pharmaceutical companies, and CROs/CMOs engaged in nucleoside chemistry and drug discovery programs. The material is supplied with a high level of purity and consistency to meet the stringent demands of advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate RNA synthesis and viral replication mechanisms.
• Antiviral Drug Discovery: Serves as a core scaffold for designing novel therapeutics targeting RNA viruses.
• Oncology Research: Investigated for its potential to interfere with nucleotide metabolism in cancer cell lines.
• Chemical Synthesis: Employed in organic and medicinal chemistry for the preparation of more complex, modified nucleosides.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2'--C-Methyl-6-Azauridine
CAS No.	172605-95-7
Molecular Formula	C9H13N3O6
Molecular Weight	259.22 g/mol
Synonyms	2'-C-Methyl-6-azauridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione; 6-Aza-2'-C-methyluridine; 2'-Methyl-6-azauridine; 2'-C-Methyl-6-azauridine (CAS 172605-95-7); 2'-C-Methyl-6-aza-uridine
EINECS	Contact for details

Quality Control

Every batch of 2'--C-Methyl-6-Azauridine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC is provided with each shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.