Description

11-Azido-3,6,9-Trioxaundecanoic Acid is a specialized bifunctional PEG linker featuring a carboxylic acid group and a terminal azide, enabling versatile bioconjugation and click chemistry applications. This compound is critical for researchers and manufacturers requiring precise, stable, and bioorthogonal coupling strategies. It is primarily utilized in the pharmaceutical, biotech, and advanced materials sectors for drug delivery system development, surface functionalization, and polymer synthesis.

Application

• Bioconjugation and Click Chemistry: Acts as a key linker for coupling biomolecules (e.g., peptides, antibodies, oligonucleotides) via its azide group in copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.
• PEGylation Reagent: Used to introduce hydrophilic polyethylene glycol (PEG) spacers to drugs, proteins, or nanoparticles to enhance solubility, stability, and circulation time.
• Polymer and Dendrimer Synthesis: Serves as a functional monomer or cross-linking agent for creating smart polymers, hydrogels, and dendritic structures with tailored properties.
• Surface Modification: Facilitates the functionalization of solid surfaces (e.g., gold, silica, polymers) for biosensor development, diagnostic assays, and cell culture substrates.
• Drug Delivery System (DDS) Fabrication: Enables the construction of targeted drug carriers, micelles, and liposomes by conjugating targeting ligands or therapeutic payloads.
• Probe and Diagnostic Agent Development: Used to synthesize fluorescent, radioactive, or magnetic imaging probes for in vitro and in vivo diagnostics.

Basic Information

Product Name	11-Azido-3,6,9-Trioxaundecanoic Acid
CAS No.	172531-37-2
Molecular Formula	C10H19N3O5
Molecular Weight	261.28 g/mol
Synonyms	Azido-PEG3-Acid; 3,6,9-Trioxaundecanedioic acid, 11-azido-; 11-Azido-3,6,9-trioxaundecanoic acid; Azido-PEG3-propionic acid; 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]acetic acid; N3-PEG3-COOH; Azido-tri(ethylene glycol)-acetic acid; Azido-PEG3-acid
EINECS	Contact for details

Quality Control

Our 11-Azido-3,6,9-Trioxaundecanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Keep away from strong acids, bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.