Description

N3-Peg3-Ch2Cootbu CAS NO 172531-36-1 is a specialized bifunctional PEG linker featuring an azide (N3) group and a protected carboxylic acid (t-butyl ester) for controlled bioconjugation and material surface modification. This compound is essential for researchers and manufacturers requiring precise, stable, and bio-orthogonal crosslinking strategies in advanced material science and life sciences. It is primarily utilized in the development of antibody-drug conjugates (ADCs), hydrogel networks, and functionalized nanoparticles for targeted drug delivery and diagnostic applications.

Application

• Key intermediate in the synthesis of Antibody-Drug Conjugates (ADCs) and other biopharmaceuticals.
• Controlled crosslinking agent for creating PEG-based hydrogels with tunable mechanical properties.
• Surface functionalization of nanoparticles, quantum dots, and biosensors to enhance biocompatibility and targeting.
• Building block in peptide and protein modification via click chemistry (CuAAC or SPAAC) reactions.
• Preparation of polymer-drug conjugates for improved pharmacokinetics and reduced systemic toxicity.
• Development of diagnostic reagents and imaging probes for in vitro and in vivo applications.
• Material science applications for creating functional coatings and bio-interfaces.

Basic Information

Product Name	N3-Peg3-Ch2Cootbu
CAS No.	172531-36-1
Molecular Formula	C17H32N4O7
Molecular Weight	404.46 g/mol
Synonyms	1-Azido-3,6,9,12-tetraoxapentadecan-15-oic acid tert-butyl ester; 15-Azido-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester; Azido-PEG3-t-butyl ester; N3-PEG3-COOtBu; tert-Butyl 15-azido-4,7,10,13-tetraoxapentadecanoate; Azido-PEG3-acid t-butyl ester; PEG3 azide t-butyl ester; Azido-triethylene glycol-t-butyl ester
EINECS	Contact for details

Quality Control

Our N3-Peg3-Ch2Cootbu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for critical research and GMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. For long-term storage under inert atmosphere, keep the container sealed under nitrogen or argon. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.