Description

Ilaprazole CAS NO 172152-36-2 is a proton pump inhibitor (PPI) belonging to the benzimidazole class of compounds. It is a key active pharmaceutical ingredient (API) valued for its potent and long-lasting suppression of gastric acid secretion. This compound is essential for the research, development, and commercial manufacturing of advanced pharmaceutical formulations. It is primarily utilized by pharmaceutical companies and research institutions focused on gastroenterology and acid-related disorders.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of prescription medications for the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
• Drug Formulation Development: Used in R&D for creating novel dosage forms such as enteric-coated tablets, delayed-release capsules, and combination therapies.
• Clinical Research: Serves as a reference standard and raw material in preclinical and clinical studies to evaluate efficacy, pharmacokinetics, and safety profiles.
• Generic Drug Manufacturing: Critical for producing cost-effective generic versions of ilaprazole-based medications following patent expiration.
• Analytical Testing: Employed as a high-purity standard in quality control laboratories for HPLC, LC-MS, and other analytical method development and validation.
• Chemical Synthesis Intermediate: Used in the synthesis of more complex molecules or derivative compounds within medicinal chemistry programs.

Basic Information

Product Name	Ilaprazole
CAS No.	172152-36-2
Molecular Formula	C19H18N4O2S
Molecular Weight	366.44 g/mol
Synonyms	2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole; IY-81149; (R)-(+)-Ilaprazole; NX-197; Ilaprazole free base; Ilaprazole API
EINECS	Contact for details

Quality Control

Our Ilaprazole is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and LC-MS. We provide full traceability and support regulatory submissions with comprehensive documentation. Certificates of Analysis (COA) detailing all test results are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.