Description

4-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-4-Deoxy-Dimethyl Acetal L-Mannose is a sophisticated nucleoside analogue building block of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in the synthesis of modified nucleosides and nucleotide-based prodrugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analogues targeting viral polymerases.
• Antiviral Drug Research: Used in the development of potential treatments for viral infections such as hepatitis and herpes.
• Oncology Research: Serves as a building block for creating nucleotide prodrugs designed to inhibit cancer cell proliferation.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate nucleoside metabolic pathways.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under GMP conditions.

Basic Information

Product Name	4-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-4-Deoxy-Dimethyl Acetal L-Mannose
CAS No.	171877-93-3
Molecular Formula	C₁₄H₁₉N₅O₆
Molecular Weight	353.33 g/mol
Synonyms	9-[4,6-O-(Dimethylacetal)-2,5-anhydro-4-deoxy-β-L-mannofuranosyl]adenine; 2',3'-Dideoxy-2',3'-secoadenosine dimethyl acetal; L-Mannose, 4-(6-amino-9H-purin-9-yl)-2,5-anhydro-4-deoxy-, dimethyl acetal; 4-(6-Aminopurin-9-yl)-2,5-anhydro-4-deoxy-L-mannose dimethyl acetal; Adenine L-mannose derivative CAS 171877-93-3
EINECS	Contact for details

Quality Control

Our production of 4-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-4-Deoxy-Dimethyl Acetal L-Mannose adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are provided and can be tailored to meet the requirements of cGMP/GLP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing desiccated at -20°C. The material may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.