Description

3-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-3-Deoxy-L-Mannitol is a specialized nucleoside analogue, a key building block in medicinal chemistry and life science research. Its unique structure makes it a valuable intermediate for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside-based therapeutics. This high-purity compound is essential for pharmaceutical R&D, biotechnology, and academic research focused on nucleotide chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Agent Development: Investigated for the creation of new therapeutic agents targeting viral polymerases and reverse transcriptases.
• Academic Research: Employed in universities and research institutes for studying nucleoside chemistry and its biological implications.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-3-Deoxy-L-Mannitol
CAS No.	171877-91-1
Molecular Formula	C11H14N6O3
Molecular Weight	278.27 g/mol
Synonyms	9-(2,5-Anhydro-3-deoxy-β-L-mannofuranosyl)adenine; 2',3'-Dideoxy-2',3'-secoadenosine; 2,5-Anhydro-3-deoxy-1-(6-aminopurin-9-yl)-L-mannitol; L-2,5-Anhydro-3-deoxy-1-(6-aminopurin-9-yl)mannitol; Adenine, 9-(2,5-anhydro-3-deoxy-β-L-mannofuranosyl)-; 3'-Deoxy-2',3'-secoadenosine; Nucleoside Analogue Intermediate
EINECS	Contact for details

Quality Control

Our 3-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-3-Deoxy-L-Mannitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.