Description

3'-Deoxy-3'-Fluoro-β-D-Xylo-Inosine is a fluorinated nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a key intermediate in the synthesis of novel antiviral and anticancer agents, particularly in the development of modified oligonucleotides and nucleotide prodrugs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates for innovative therapeutic programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Antiviral Drug Research: Used in the development of potential therapeutics targeting viral polymerases, including for hepatitis and other viral infections.
• Oncology Research: Serves as a building block for creating nucleoside-based chemotherapeutic agents and targeted cancer therapies.
• Oligonucleotide Synthesis: Employed in the production of modified antisense oligonucleotides and siRNA molecules for genetic research and therapeutic applications.
• Biochemical Research: Used as a tool compound to study enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Process Development: Serves as a reference standard and intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-β-D-Xylo-Inosine
CAS No.	171667-46-2
Molecular Formula	C10H11FN4O4
Molecular Weight	270.22 g/mol
Synonyms	3'-Deoxy-3'-fluoroinosine; 3'-Fluoro-3'-deoxyinosine; 9-[(3-Deoxy-3-fluoro-β-D-xylofuranosyl)]hypoxanthine; 3'-F-3'-dI; 3'-Fluoro-3'-deoxy-β-D-xylo-inosine; 3'-Fluoro-3'-deoxyinosine (β-D-xylo configuration); 171667-46-2
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-β-D-Xylo-Inosine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.