Description

(R)-(+)-Rabeprazole Sodium CAS NO 171440-18-9 is the sodium salt of the pharmacologically active R-enantiomer of rabeprazole, a proton pump inhibitor (PPI). This high-purity chiral intermediate is critical for the development and manufacturing of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical companies and research institutions focused on advanced gastrointestinal therapeutics, chiral drug synthesis, and novel formulation development.

Application

• Key chiral intermediate for the synthesis of enantiomerically pure Rabeprazole and related proton pump inhibitor APIs.
• Active pharmaceutical ingredient (API) in the development of targeted gastrointestinal drugs for acid-related disorders.
• Critical reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Starting material for pharmacological and clinical research studying the specific effects of the (R)-enantiomer.
• Used in formulation R&D for stable and bioavailable dosage forms, such as enteric-coated tablets or delayed-release capsules.
• Building block in organic synthesis for creating novel chemical entities with potential therapeutic value.

Basic Information

Product Name	(R)-(+)-Rabeprazole Sodium
CAS No.	171440-18-9
Molecular Formula	C18H20N3NaO3S
Molecular Weight	381.42 g/mol
Synonyms	(R)-Rabeprazole Sodium; Dexrabeprazole Sodium; (+)-Rabeprazole Sodium; (R)-(+)-2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sodium Salt; Sodium (R)-(+)-rabeprazole; Pariet (enantiomer); Aciphex (enantiomer)
EINECS	Contact for details

Quality Control

Our (R)-(+)-Rabeprazole Sodium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and impurity profiling by HPLC, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided and can be tailored to meet specific pharmacopeial standards (e.g., USP, EP, JP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥98.5%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.