Description

Oritavancin is a semi-synthetic lipoglycopeptide antibiotic derived from a chloroeremomycin complex. This compound is a critical active pharmaceutical ingredient (API) valued for its potent bactericidal activity against Gram-positive pathogens, including multidrug-resistant strains. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of advanced antibiotic formulations targeting serious skin structure infections and other complex bacterial diseases.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of injectable antibiotic drugs.
• Research and development of novel antimicrobial therapies and combination treatments.
• Reference standard in analytical laboratories for quality control and method validation.
• Pre-clinical and clinical studies investigating efficacy against resistant bacterial infections.
• Production of pharmaceutical intermediates for further chemical synthesis.
• Component in microbiological research for studying glycopeptide mechanisms of action.

Basic Information

Product Name	Oritavancin
CAS No.	171099-57-3
Molecular Formula	C86H97Cl3N10O26
Molecular Weight	1793.10 g/mol
Synonyms	LY 333328; Oritavancin diphosphate; N'''-[(3S,6R,9R,12R,15S,18R,21S,24S,30S,33S)-30-[(2R,3R,4R,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-6-[(2R,4S,5S,6S)-5-amino-4,6-dihydroxyoxan-2-yl]oxy-9,15,18-tris(4-aminobenzyl)-12-[(1R)-1-hydroxyethyl]-3,21,24-tris(4-hydroxybenzyl)-2,5,8,11,14,17,20,23,26,29,32-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecazatricyclo[31.3.0.04,9]hexatriacontan-33-yl]-3-(4-chlorobenzyl)-4-hydroxy-5,5-dimethyl-2-oxoimidazolidine-1-carboxamide; (4''R)-4''-epi-vancomycin; Orbactiv API
EINECS	Contact for details

Quality Control

Our Oritavancin is manufactured under strict quality systems to ensure it meets the high-purity standards required for pharmaceutical use. Each batch is subjected to comprehensive analytical testing, including identity, purity, and impurity profile analysis, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing all test results is provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Microbial Enumeration	Conforms to EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.