Description

4'-C-Fluoroadenosine is a fluorinated nucleoside analog, a key building block in medicinal chemistry and biochemical research. Its strategic fluorination at the 4'-carbon position of the ribose ring significantly alters its biological activity and metabolic stability, making it a valuable precursor for developing novel therapeutics and research probes. This compound is primarily utilized by pharmaceutical R&D teams and academic researchers working on antiviral agents, anticancer drug candidates, and as a tool for studying nucleoside metabolism and enzyme mechanisms.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the function of kinases, polymerases, and other nucleoside-processing enzymes.
• Proteomics & Molecular Biology: Serves as a building block for synthesizing modified oligonucleotides and probes for diagnostic applications.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by introducing fluorine to modulate the potency, selectivity, and pharmacokinetic properties of lead compounds.
• Academic Research: Employed in universities and research institutes for fundamental studies on nucleic acid chemistry and drug discovery pathways.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4'-C-Fluoroadenosine
CAS No.	170874-47-2
Molecular Formula	C10H12FN5O4
Molecular Weight	285.23 g/mol
Synonyms	4'-Fluoroadenosine; 4'-Deoxy-4'-fluoroadenosine; 9-[(2R,3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-amine; Adenosine, 4'-deoxy-4'-fluoro-; 4'-C-Fluoro-adenosine; 4'-Fluoro-adenosine; 4'-F-Ado
EINECS	Contact for details

Quality Control

Our 4'-C-Fluoroadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.