Description

Efaproxiral Sodium is a synthetic, small-molecule radiosensitizer used to enhance the efficacy of radiation therapy. Its primary value lies in its ability to increase tumor oxygenation, thereby making hypoxic cancer cells more susceptible to radiation damage. This compound is of significant interest to pharmaceutical manufacturers and research institutions developing advanced oncology treatments. It is supplied as a high-purity active pharmaceutical ingredient (API) for formulation into clinical and research-grade products.

Application

• Oncological Research: A key investigational agent in preclinical and clinical studies for enhancing the effects of radiotherapy on solid tumors.
• Pharmaceutical Development: Serves as the active pharmaceutical ingredient (API) in the formulation of novel radiosensitizing drugs.
• Radiation Therapy Adjunct: Used to potentiate the tumoricidal effects of radiation in cancers known to have hypoxic regions, such as brain, lung, and head & neck cancers.
• Mechanistic Studies: Employed in biochemical research to study oxygen transport and hypoxia-related pathways in cancer biology.
• Combination Therapy Development: Investigated in conjunction with chemotherapy and other treatment modalities to improve overall therapeutic outcomes.

Basic Information

Product Name	Efaproxiral Sodium
CAS No.	170787-99-2
Molecular Formula	C14H19Br2NaO4
Molecular Weight	434.10 g/mol
Synonyms	Efaproxiral Sodium; RSR13, Sodium Salt; 2-[4-[(2-Bromo-1-oxopropyl)oxy]-3,5-dibromophenyl]acetic Acid Sodium Salt; B-104; NSC 726189; RSR-13; Oxobromin; Efalex
EINECS	Contact for details

Quality Control

Our Efaproxiral Sodium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.