Description

[R-(R*,S*)]-9-Cyano-6-(2-Cyanoethoxy)-3-(1-Hydroxyhexadecyl)-5,7-Dioxa-2-Aza-6-Phosphanonanoic Acid 6-Oxide 1,1-Dimethylethyl Ester is a high-purity, complex organic intermediate featuring a unique phosphonate ester and cyanoalkyl ether structure. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Prodrug Synthesis: Utilized in the design and development of prodrugs to enhance bioavailability and targeted delivery of active molecules.
• Phosphonate Chemistry Research: Serves as a versatile precursor in medicinal chemistry for introducing phosphonate or phosphate mimetics into lead compounds.
• Agrochemical Development: Intermediate in the research phase for creating new generation herbicides or plant growth regulators with specific activity.
• Ligand and Catalyst Development: Potential use in the development of specialized ligands for asymmetric catalysis or metal complexation.
• Polymer Modification: Can be used to introduce functional groups into specialty polymers for advanced material science applications.

Basic Information

Item	Details
Product Name	[R-(R*,S*)]-9-Cyano-6-(2-Cyanoethoxy)-3-(1-Hydroxyhexadecyl)-5,7-Dioxa-2-Aza-6-Phosphanonanoic Acid 6-Oxide 1,1-Dimethylethyl Ester
CAS No.	169528-22-7
Molecular Formula	C31H56N3O7P
Molecular Weight	613.77 g/mol
Synonyms	tert-Butyl (9R)-9-cyano-6-[2-cyanoethoxy(oxido)phosphoryl]-3-(1-hydroxyhexadecyl)-5,7-dioxa-2-aza-6-phosphanonanoate 6-oxide; (R)-tert-Butyl 9-cyano-6-((2-cyanoethoxy)(oxido)phosphoryl)-3-(1-hydroxyhexadecyl)-5,7-dioxa-2-aza-6-phosphanonanoate 6-oxide; Phosphonate Ester Intermediate 169528-22-7; 1,1-Dimethylethyl (R)-9-cyano-6-[(2-cyanoethoxy)hydroxyphosphinyl]-3-(1-hydroxyhexadecyl)-5,7-dioxa-2-aza-6-phosphanonanoate 6-oxide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [R-(R*,S*)]-9-Cyano-6-(2-Cyanoethoxy)-3-(1-Hydroxyhexadecyl)-5,7-Dioxa-2-Aza-6-Phosphanonanoic Acid 6-Oxide 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content to ensure it meets the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.