Description

3-Pyridinecarbonyl Chloride, 2-Methyl- (9Ci) is a versatile and reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-methylnicotinoyl moiety, a key structural motif in pharmaceutical and agrochemical research. This high-purity intermediate is essential for medicinal chemists and process development scientists working on novel active ingredients. Its reliable quality and consistent performance make it a trusted reagent for constructing complex molecules in regulated environments.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides that require the nicotinic acid derivative structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials where the pyridine core imparts specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A crucial reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
• Academic and R&D Laboratories: Used in fundamental research for exploring new chemical reactions and synthesizing novel heterocyclic compounds for biological screening.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 2-Methyl- (9Ci)
CAS No.	169229-06-5
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	2-Methylnicotinoyl chloride; 2-Methyl-3-pyridinecarbonyl chloride; 2-Methylpyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 2-methyl-; 2-Methylnicotinic acid chloride; 2-Methyl-3-carboxypyridine chloride; 2-Picoline-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonyl Chloride, 2-Methyl- (9Ci) is produced and tested under a strict quality management system to ensure it meets the high standards required for research and commercial synthesis. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) documenting batch-specific results are available upon request, providing full traceability and assurance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.