Description

Acetamide, n-[[(5S)-3-[3-Fluoro-4-(1-Oxido-4-Thiomorpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel oxazolidinone-class antibacterial agents, offering a key building block for targeted drug development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in producing next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel oxazolidinone antibiotics.
• Antibacterial Agent Research: Used in medicinal chemistry for the development and optimization of new antibacterial compounds targeting resistant pathogens.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex molecules with specific biological activity.
• Active Pharmaceutical Ingredient (API) Development: A key starting material or intermediate in the process development and scale-up of new API candidates.
• Biochemical Research: Utilized in studies investigating structure-activity relationships (SAR) of antimicrobial agents.

Basic Information

Product Name	Acetamide, n-[[(5S)-3-[3-Fluoro-4-(1-Oxido-4-Thiomorpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]-
CAS No.	168828-60-2
Molecular Formula	C16H20FN3O4S
Molecular Weight	369.41 g/mol
Synonyms	N-[[(5S)-3-[3-Fluoro-4-(1-Oxido-4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; (5S)-N-Acetoxymethyl-3-(3-fluoro-4-(1-oxothiomorpholino)phenyl)-2-oxazolidinone; Oxazolidinone antibacterial intermediate; TD-1792 intermediate; Related to Radezolid intermediate; Thiomorpholine sulfoxide derivative; Fluorophenyl oxazolidinone acetamide.
EINECS	Contact for details

Quality Control

Our Acetamide, n-[[(5S)-3-[3-Fluoro-4-(1-Oxido-4-Thiomorpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]- is manufactured under strict quality systems suitable for pharmaceutical R&D. All batches undergo rigorous analytical testing, including chiral HPLC for enantiomeric purity and comprehensive impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (5S enantiomer)
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.