Description

4',2,2-Trimethylbutyrophenone is a specialized organic compound belonging to the aromatic ketone class, serving as a valuable intermediate in advanced chemical synthesis. Its unique trimethyl-substituted structure makes it a critical building block for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical sectors seeking reliable and consistent raw materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for compounds requiring a hindered butyrophenone backbone.
• Fine Chemical Synthesis: Used as a versatile building block in the multi-step synthesis of complex organic molecules, including ligands, catalysts, and specialty polymers.
• Agrochemical Research: Employed in the development of novel crop protection agents and herbicides, where its structural motif can contribute to specific biological activity.
• Material Science: Acts as a precursor or monomer in the development of advanced polymeric materials with specific thermal or optical properties.
• Chemical Research & Development: Serves as a standard or starting material in methodological development and exploratory organic chemistry within academic and industrial R&D settings.

Basic Information

Product Name	4',2,2-Trimethylbutyrophenone
CAS No.	167760-72-7
Molecular Formula	C13H18O
Molecular Weight	190.28 g/mol
Synonyms	1-(4-Methylphenyl)-2,2-dimethyl-1-butanone; 4-Methyl-2,2-dimethylbutyrophenone; p-Methyl-α,α-dimethylbutyrophenone; 2,2-Dimethyl-1-(p-tolyl)-1-butanone; Butyrophenone, 4',2,2-trimethyl-; 1-(4-Methylphenyl)-2,2-dimethylbutan-1-one
EINECS	Contact for details

Quality Control

Our 4',2,2-Trimethylbutyrophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current industry best practices, and our quality systems support compliance with relevant guidelines for pharmaceutical intermediates and fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.