Description

3-Acetoxy-2-Methylbenzoyl Chloride is a high-purity, reactive organic intermediate characterized by its acid chloride functionality. This compound is critical for introducing the 3-acetoxy-2-methylbenzoyl moiety into target molecules, enabling efficient synthesis in advanced chemical processes. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for anti-inflammatory and analgesic drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its benzoyl chloride structure acts as a versatile coupling agent.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers requiring specific aromatic ester functionalities.
• Research & Development: Essential reagent in organic chemistry laboratories for method development and creating custom molecular libraries for screening.
• Peptide Modification: Employed in biochemical research for acylating amino groups or modifying peptide structures under controlled conditions.

Basic Information

Product Name	3-Acetoxy-2-Methylbenzoyl Chloride
CAS No.	167678-46-8
Molecular Formula	C11H11ClO3
Molecular Weight	226.66 g/mol
Synonyms	2-Methyl-3-acetoxybenzoyl chloride; 3-(Acetyloxy)-2-methylbenzoyl chloride; o-Acetoxy-m-toluoyl chloride; 2-Methyl-3-(acetyloxy)benzoyl chloride; 3-Acetoxy-o-toluoyl chloride; (3-Acetoxy-2-methylphenyl)carbonyl chloride; Benzoyl chloride, 3-(acetyloxy)-2-methyl-
EINECS	Contact for details

Quality Control

Our 3-Acetoxy-2-Methylbenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Isolate from incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.