Description

Pentacyclo[4.2.0.02,5.03,8.04,7]Octanecarbonyl Chloride, 4-Fluoro- (9Ci) is a highly functionalized, strained polycyclic organic building block featuring a reactive acid chloride group and a fluorine substituent. This compound is valued for its unique three-dimensional geometry and dual reactivity, enabling the synthesis of complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical and advanced materials sectors for developing novel active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides with enhanced biological activity and stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent for high-performance polymers with specific thermal or optical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to construct sophisticated, sterically demanding ligands for asymmetric catalysis.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the reactive acyl chloride moiety and the fluorine tag for potential 18F radiolabeling studies.
• Academic & R&D: A valuable reagent for methodological studies in synthetic organic chemistry focused on strained ring systems and fluorine chemistry.

Basic Information

Product Name	Pentacyclo[4.2.0.02,5.03,8.04,7]Octanecarbonyl Chloride, 4-Fluoro- (9Ci)
CAS No.	167496-69-7
Molecular Formula	C9H6ClFO
Molecular Weight	184.59 g/mol
Synonyms	4-Fluoropentacyclo[4.2.0.02,5.03,8.04,7]octane-1-carbonyl chloride; 4-Fluorocubane-1-carbonyl chloride; 1-(Chlorocarbonyl)-4-fluoropentacyclo[4.2.0.02,5.03,8.04,7]octane; 4-Fluorocubanecarboxylic acid chloride; Fluorinated cubane carbonyl chloride
EINECS	Contact for details

Quality Control

Our Pentacyclo[4.2.0.02,5.03,8.04,7]Octanecarbonyl Chloride, 4-Fluoro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and custom purity grades or analytical packages can be discussed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactive acid chloride group, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.