Description

2-Fluoro-4-(Trifluoromethoxy)Benzoyl Chloride, 97% is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of both fluorine and trifluoromethoxy functional groups, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides that leverage fluorine chemistry for improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated aromatic cores for advanced electronic materials in displays and lighting.
• Polymer Modification: Serves as a monomer or grafting agent to introduce fluorinated aromatic units into polymers, enhancing chemical resistance and thermal stability.
• Custom Synthesis & Contract Research: A valuable reagent for fine chemical and custom synthesis organizations (CROs/CMOs) serving the life sciences sector.
• Fluorinated Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethoxy)Benzoyl Chloride, 97%
CAS No.	166948-50-1
Molecular Formula	C8H3ClF4O2
Molecular Weight	242.56 g/mol
Synonyms	2-Fluoro-4-(trifluoromethoxy)benzoic acid chloride; 4-(Trifluoromethoxy)-2-fluorobenzoic acid chloride; 2-Fluoro-α,α,α-trifluoro-p-methoxybenzoyl chloride; 2-Fluoro-4-trifluoromethoxybenzoyl chloride; Benzoic acid, 2-fluoro-4-(trifluoromethoxy)-, chloride; 166948-50-1; 2-Fluoro-4-(trifluoromethoxy)benzoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethoxy)Benzoyl Chloride, 97% is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.