Description

Diethyl 5-Oxopentylphosphonate is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a versatile and critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective construction of complex molecules. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for the synthesis of active pharmaceutical ingredients (APIs), novel crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via olefination reactions.
• Agrochemical Synthesis: Used in the development and production of novel herbicides, insecticides, and plant growth regulators.
• Specialty Chemical Manufacturing: Serves as a building block for creating functional materials, ligands for catalysis, and advanced polymers.
• Academic & Industrial R&D: A valuable reagent in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	Diethyl 5-Oxopentylphosphonate
CAS No.	166528-15-0
Molecular Formula	C9H19O4P
Molecular Weight	222.22 g/mol
Synonyms	5-Oxopentylphosphonic Acid Diethyl Ester; Diethyl (5-Oxopentyl)phosphonate; Diethyl 4-Oxobutylphosphonate (common misnomer); 5-Oxoamylphosphonic Acid Diethyl Ester; (5-Oxopentyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, (5-Oxopentyl)-, Diethyl Ester; HWE Reagent Intermediate
EINECS	Contact for details

Quality Control

Our Diethyl 5-Oxopentylphosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The product may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.