Description

7-Deaza-7-Iodo-2'-Deoxyadenosine is a modified nucleoside analog, specifically engineered for advanced biochemical and pharmaceutical research. This compound is a critical building block in the development of oligonucleotide probes and therapeutic agents, offering unique properties for modulating nucleic acid interactions. It is primarily utilized by researchers and manufacturers in the fields of antiviral drug discovery, molecular diagnostics, and nucleotide chemistry.

Application

• Antiviral Drug Development: Acts as a key intermediate in the synthesis of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral compounds.
• Molecular Biology Research: Used in the synthesis of modified oligonucleotides for probing nucleic acid structure, function, and enzyme mechanisms.
• Diagnostic Probe Synthesis: Incorporated into DNA/RNA probes to enhance stability and specificity in diagnostic assays like FISH and PCR.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in oncology and virology research programs.
• Biochemical Tool Development: Employed in the study of DNA repair mechanisms and polymerase fidelity due to its altered base-pairing properties.

Basic Information

Product Name	7-Deaza-7-Iodo-2'-Deoxyadenosine
CAS No.	166247-63-8
Molecular Formula	C11H13IN4O3
Molecular Weight	376.15 g/mol
Synonyms	7-Iodo-7-deaza-2'-deoxyadenosine; 7-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 2-deoxy-β-D-erythro-pentofuranosyl-; 7-Deaza-7-iodo-dA; 7-Iodo-tubercidin 2'-deoxyriboside; 2'-Deoxy-7-iodotubercidin; 7-Iodo-2'-deoxy-7-deazaadenosine; 7-Iodo-7-deazaadenosine 2'-deoxyriboside
EINECS	Contact for details

Quality Control

Our 7-Deaza-7-Iodo-2'-Deoxyadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.