Description

5-Quinolinecarbonyl Chloride, 8-Hydroxy- (9Ci) is a specialized quinoline derivative that serves as a high-value synthetic intermediate. This compound is critical for the development of complex molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting neurological or anti-infective pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides with quinoline-based active ingredients.
• Ligand Synthesis: Serves as a precursor for creating complex chelating agents and catalysts used in asymmetric synthesis and metal coordination chemistry.
• Material Science: Intermediate in the production of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) components.
• Fluorescent Probe Development: Utilized to synthesize quinoline-based fluorophores for biochemical sensing and imaging applications.
• Academic & Contract Research: Essential reagent for methodological studies and novel reaction development in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-Quinolinecarbonyl Chloride, 8-Hydroxy- (9Ci)
CAS No.	166242-16-6
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	8-Hydroxyquinoline-5-carbonyl chloride; 5-(Chlorocarbonyl)-8-hydroxyquinoline; 8-Hydroxy-5-quinolinecarboxylic acid chloride; 5-Carboxy-8-hydroxyquinoline chloride; 8-Hydroxy-5-quinolinecarbonyl chloride; 5-Quinolinecarbonyl chloride, 8-hydroxy-
EINECS	Contact for details

Quality Control

Our production of 5-Quinolinecarbonyl Chloride, 8-Hydroxy- (9Ci) adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.