Description

Piperazine, 1-(2-Isothiocyanatoethyl)- (9Ci) is a specialized heterocyclic organic compound featuring a reactive isothiocyanate group, making it a valuable bifunctional building block for chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds to develop advanced materials and bioactive molecules. It is primarily utilized in pharmaceutical research, agrochemical development, and as a key intermediate in the synthesis of complex chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and anti-infective pathways.
• Bioconjugation Reagent: Used to modify proteins, peptides, and antibodies by reacting with amine groups, enabling the creation of targeted drug delivery systems and diagnostic probes.
• Agrochemical Synthesis: Acts as a key building block for developing new pesticides and herbicides with specific modes of action.
• Polymer Chemistry: Employed in the production of specialty polymers, resins, and coatings where the piperazine ring contributes to thermal stability and mechanical properties.
• Material Science Research: Utilized in the development of advanced organic frameworks and functional materials.
• Chemical Biology Probes: Facilitates the creation of activity-based probes for studying enzyme function and cellular processes.

Basic Information

Item	Detail
Product Name	Piperazine, 1-(2-Isothiocyanatoethyl)- (9Ci)
CAS No.	165680-21-7
Molecular Formula	C7H11N3S
Molecular Weight	169.25 g/mol
Synonyms	1-(2-Isothiocyanatoethyl)piperazine; N-(2-Isothiocyanatoethyl)piperazine; 2-(Piperazin-1-yl)ethyl isothiocyanate; 1-Piperazineethanamine, N-(thiocyanato-κN)-; 165680-21-7; 2-Piperazin-1-ylethyl isothiocyanate; 1-(2-Isothiocyanato-ethyl)-piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(2-Isothiocyanatoethyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.