Description

Indisulam CAS NO 165668-41-7 is a synthetic sulfonamide compound that functions as a potent and selective inhibitor of carbonic anhydrase IX (CA IX). This compound is of significant interest in pharmaceutical research and development due to its targeted mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel anticancer therapeutics.

Application

• Anticancer Research: As a lead compound for investigating CA IX inhibition in various cancer models, including solid tumors.
• Biochemical Assay Development: Used as a reference standard in high-throughput screening (HTS) to identify new CA IX modulators.
• Mechanism of Action Studies: Employed in preclinical studies to understand the role of carbonic anhydrase in tumor hypoxia and acidification.
• Pharmaceutical Intermediate: Serves as a key synthetic intermediate or reference material in the development of related sulfonamide-based drug candidates.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and cancer biology.

Basic Information

Product Name	Indisulam
CAS No.	165668-41-7
Molecular Formula	C₁₆H₁₄BrN₃O₄S₂
Molecular Weight	456.34 g/mol
Synonyms	N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine; E7070; Indisulam (E7070); E 7070; JRF-104; N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine; 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
EINECS	Contact for details

Quality Control

Our Indisulam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.