Description

2-(Phenylthio)Pyridine-3-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a versatile building block, enabling the introduction of the 2-(phenylthio)pyridine moiety into complex molecular architectures. Pharmaceutical, agrochemical, and material science researchers need it for the development of novel active ingredients and functional materials, leveraging its acyl chloride functionality for efficient coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry research targeting novel small molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, where the pyridine-thioether structure can confer specific biological activity.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular components for OLEDs and sensors.
• Custom Chemical Synthesis: A critical reagent for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic and organosulfur chemistry.

Basic Information

Product Name	2-(Phenylthio)Pyridine-3-Carbonyl Chloride
CAS No.	165249-92-3
Molecular Formula	C12H8ClNOS
Molecular Weight	249.71 g/mol
Synonyms	3-Pyridinecarbonyl chloride, 2-(phenylthio)-; 2-(Phenylthio)nicotinoyl chloride; 2-(Phenylsulfanyl)pyridine-3-carbonyl chloride; 2-(Phenylthio)-3-pyridinecarbonyl chloride; 2-(Benzenethio)nicotinoyl chloride; 165249-92-3; 2-Phenylthiopyridine-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Phenylthio)Pyridine-3-Carbonyl Chloride is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and IR spectroscopy, to ensure compliance with exacting industry standards and customer specifications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.