Description

Methyl-2,3,4-Tri-o-Acetyl-β-D-Galactopyranosyluronosyl Azide is a key, high-purity glycosyl donor intermediate used in the synthesis of complex oligosaccharides and glycoconjugates. Its value lies in providing a protected, activated galacturonic acid derivative that enables precise and efficient glycosylation reactions under controlled conditions. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating carbohydrate-based vaccines, diagnostic tools, and novel therapeutics, as well as in advanced glycochemistry research.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex carbohydrate antigens and glycoconjugate vaccine candidates.
• Glycochemistry Research: Enables the study of glycosylation mechanisms and the construction of biologically active oligosaccharides for structure-activity relationship (SAR) studies.
• Diagnostic Reagent Synthesis: Used in the production of labeled glycans and probes for diagnostic assays and imaging.
• Bioconjugation: The azide functional group allows for efficient "click chemistry" reactions, facilitating the attachment of carbohydrate motifs to proteins, peptides, or surfaces.
• Enzyme Substrate Development: Serves as a substrate or inhibitor precursor for glycosidase and glycosyltransferase enzyme studies.
• Material Science: Potential use in creating functionalized surfaces or polymers with specific carbohydrate recognition properties.

Basic Information

Product Name	Methyl-2,3,4-Tri-o-Acetyl-β-D-Galactopyranosyluronosyl Azide
CAS No.	163776-36-1
Molecular Formula	C15H19N3O11
Molecular Weight	417.33 g/mol
Synonyms	Methyl (2,3,4-tri-O-acetyl-β-D-galactopyranosyluronate) azide; Methyl 2,3,4-Tri-O-acetyl-β-D-galactopyranosiduronic Azide; 1-Azido-1-deoxy-2,3,4-tri-O-acetyl-α-D-galacturonic acid methyl ester; β-D-Galactopyranosiduronic acid, methyl 2,3,4-tri-O-acetyl-, azide; Galacturonic Acid Methyl Ester Azide (Acetylated); Glycosyl Azide Donor (Galacturonic); Acetylated Galacturonosyl Azide Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl-2,3,4-Tri-o-Acetyl-β-D-Galactopyranosyluronosyl Azide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant cGMP guidelines for advanced pharmaceutical intermediates, and specifications can be aligned with client-specific requirements for research or commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.