Description

Caspofungin is a semi-synthetic lipopeptide antifungal agent belonging to the echinocandin class. It is a critical active pharmaceutical ingredient (API) valued for its potent fungicidal activity against a broad spectrum of Candida and Aspergillus species by non-competitively inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the fungal cell wall. This product is primarily required by pharmaceutical manufacturers and research institutions for the formulation of injectable antifungal medications and advanced clinical research into novel therapeutic applications.

Application

• Primary use as the Active Pharmaceutical Ingredient (API) in the manufacture of injectable antifungal drugs.
• Formulation of Caspofungin Acetate for intravenous administration in hospital settings.
• Research and development of new antifungal combination therapies and drug delivery systems.
• Reference standard in analytical laboratories for quality control and method validation.
• Preclinical and clinical studies investigating its efficacy against resistant fungal strains.
• Use in biochemical research to study fungal cell wall biosynthesis and mechanisms of action.

Basic Information

Product Name	Caspofungin
CAS No.	162808-62-0
Molecular Formula	C52H88N10O15
Molecular Weight	1093.3 g/mol
Synonyms	Caspofungin Acetate (common salt form); MK-0991; L-743,872; (1-((4R,5R)-4,5-Dihydroxy-N2-((4"-(pentyloxy)[1,1':4',1"-terphenyl]-4-yl)carbonyl)-L-ornithine)-5-((3R)-3-hydroxy-L-ornithine)pneumocandin B0; Cancidas (Brand Name); Echinocandin B Derivative; Antifungal Lipopeptide
EINECS	Contact for details

Quality Control

Our Caspofungin is manufactured and tested under strict quality systems. It is suitable for use in pharmaceutical development and production, with specifications that can meet relevant pharmacopeial standards. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure consistency and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.