Description

Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, (1S-Cis)- (9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex, stereochemically defined molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new synthetic routes and compound libraries.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, (1S-Cis)- (9Ci)
CAS No.	162776-57-0
Molecular Formula	C8H11ClO3
Molecular Weight	190.62 g/mol
Synonyms	(1S,2S)-2-(Chlorocarbonyl)cyclopentanecarboxylic acid methyl ester; Methyl (1S,2S)-2-(chlorocarbonyl)cyclopentanecarboxylate; (1S-cis)-2-(Chlorocarbonyl)cyclopentanecarboxylic Acid Methyl Ester; cis-Methyl 2-(chloroformyl)cyclopentanecarboxylate; (1S,2S)-Methyl 2-(chlorocarbonyl)cyclopentanecarboxylate; Cyclopentanecarboxylic acid, 2-(chlorocarbonyl)-, methyl ester, (1S-cis)-; (1S,2S)-2-Carbomethoxycyclopentanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, (1S-Cis)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.