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(R)-1-(2-Fluorophenyl)Ethanol CAS NO 162427-79-4
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CAS No.:162427-79-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-1-(2-Fluorophenyl)Ethanol is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. This optically active fluorinated alcohol is critical for the development of enantiomerically pure pharmaceuticals and agrochemicals, where its specific stereochemistry imparts desired biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for the production of active pharmaceutical ingredients (APIs), chiral ligands, and specialty chemicals.
Application
- Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutics.
- Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the (R)-enantiomer provides targeted biological efficacy.
- Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
- Fine Chemical & Flavor/Fragrance Intermediate: Employed in the synthesis of complex fluorinated aroma chemicals and specialty fine chemicals.
- Academic & Industrial Research: A valuable compound for methodological development in organic synthesis and stereochemistry studies.
- Material Science: Potential monomer or building block for creating chiral polymers and advanced functional materials.
Basic Information
| Product Name | (R)-1-(2-Fluorophenyl)Ethanol |
| CAS No. | 162427-79-4 |
| Molecular Formula | C8H9FO |
| Molecular Weight | 140.16 g/mol |
| Synonyms | (R)-1-(2-Fluorophenyl)ethanol; (R)-α-Methyl-2-fluorobenzyl alcohol; (R)-2-Fluoro-α-methylbenzyl alcohol; (1R)-1-(2-Fluorophenyl)ethan-1-ol; (R)-(-)-1-(2-Fluorophenyl)ethanol; (R)-1-(o-Fluorophenyl)ethanol; (R)-2-Fluorophenylmethylcarbinol; (R)-FMPE |
| EINECS | Contact for details |
Quality Control
Our (R)-1-(2-Fluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability and chiral integrity.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 0.5% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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