Description

Cyclopropanecarbonyl Chloride, 2,2,3-Trimethyl-, cis- (9Ci) is a specialized, high-purity organochloride building block essential for advanced synthetic chemistry. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce the unique steric and electronic properties of the cis-trimethylcyclopropane moiety into target structures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane ring can confer specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers or functional additives for polymers and advanced materials with tailored properties.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 2,2,3-Trimethyl-, cis- (9Ci)
CAS No.	162224-57-9
Molecular Formula	C7H11ClO
Molecular Weight	146.62 g/mol
Synonyms	cis-2,2,3-Trimethylcyclopropanecarbonyl chloride; (1S,2S)-2,2,3-Trimethylcyclopropane-1-carbonyl chloride; 2,2,3-Trimethylcyclopropanecarboxylic acid chloride, cis-; (1R,2R)-2,2,3-Trimethylcyclopropane-1-carbonyl chloride; Trimethylcyclopropanecarbonyl chloride; Cyclopropanecarboxylic acid, 2,2,3-trimethyl-, chloride, cis-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2,2,3-Trimethyl-, cis- (9Ci) is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.