Description

Esomeprazole Magnesium is the magnesium salt form of the proton pump inhibitor (PPI) esomeprazole, the (S)-enantiomer of omeprazole. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of delayed-release oral dosage forms designed to effectively reduce gastric acid secretion. It is primarily required by pharmaceutical manufacturers for the production of medications treating gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Our supply of Esomeprazole Magnesium CAS NO 161973-10-0 is manufactured under strict quality control to ensure batch-to-batch consistency and regulatory compliance.

Application

• Pharmaceutical API: Core active ingredient in prescription and generic medications for acid-related disorders.
• GERD Treatment: Formulated into delayed-release capsules and tablets for the healing and maintenance of erosive esophagitis.
• Peptic Ulcer Therapy: Used in combination therapies for the treatment and prevention of duodenal and gastric ulcers.
• Zollinger-Ellison Syndrome Management: Employed in high-dose formulations for the long-term control of pathological hypersecretory conditions.
• Generic Drug Manufacturing: Sourced by generic pharmaceutical companies for bioequivalent product development.
• Clinical Research: Used as a reference standard or raw material in bioavailability and pharmacokinetic studies.

Basic Information

Product Name	Esomeprazole Magnesium
CAS No.	161973-10-0
Molecular Formula	C34H36MgN6O6S2
Molecular Weight	713.12 g/mol
Synonyms	Esomeprazole Mg; (S)-Omeprazole Magnesium; Esomeprazole Magnesium Trihydrate; Nexium® API; Magnesium bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl]-1H-benzimidazol-1-ide); Perprazole Magnesium; H 199/18 Magnesium Salt
EINECS	Contact for details

Quality Control

Our Esomeprazole Magnesium is produced in facilities adhering to current Good Manufacturing Practices (cGMP). Each batch is subjected to a comprehensive battery of tests including identification, assay, impurity profiling (including related substances and enantiomeric purity), and residual solvent analysis to ensure it meets stringent pharmacopeial standards (USP/EP). A Certificate of Analysis (COA) documenting all specifications and results is provided with every shipment to guarantee traceability and quality assurance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The original container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (on anhydrous basis)	98.0% - 102.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Enantiomeric Purity (HPLC)	≥ 99.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.