Description

1H-2-Benzothiopyran-1-Carbonyl Chloride, 3,4-Dihydro- (9Ci) is a specialized heterocyclic building block featuring a reactive acid chloride functional group fused to a thiopyran ring system. This compound is a critical intermediate for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. Its unique structure enables the efficient introduction of the 1H-2-benzothiopyran moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system or metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the benzothiopyran scaffold can contribute to unique biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the research of advanced polymers or organic electronic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function or cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1H-2-Benzothiopyran-1-Carbonyl Chloride, 3,4-Dihydro- (9Ci)
CAS No.	161744-20-3
Molecular Formula	C10H7ClOS
Molecular Weight	210.68 g/mol
Synonyms	3,4-Dihydro-1H-2-benzothiopyran-1-carbonyl chloride; 3,4-Dihydro-2H-1-benzothiopyran-1-carbonyl chloride; 1-Chlorocarbonyl-3,4-dihydro-1H-2-benzothiopyran; 2H-1-Benzothiopyran-1-carbonyl chloride, 3,4-dihydro-; 1H-2-Benzothiopyran-1-carbonyl chloride, 3,4-dihydro-; 161744-20-3; Benzothiopyran carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our production of 1H-2-Benzothiopyran-1-Carbonyl Chloride, 3,4-Dihydro- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. We employ advanced analytical techniques, including HPLC, GC, NMR, and IR spectroscopy, for comprehensive characterization and purity verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.