Description

N4,5'-o-Dibenzoyl-2'-Deoxycytidine is a key protected nucleoside derivative, specifically designed for advanced oligonucleotide synthesis and pharmaceutical research. This compound is critical for researchers and manufacturers requiring high-purity intermediates to ensure the integrity and yield of complex nucleotide sequences. It is primarily utilized in the development of antisense oligonucleotides, siRNA, and other therapeutic nucleic acid analogs, making it essential for biotechnology, pharmaceutical R&D, and fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in solid-phase and solution-phase synthesis for the controlled assembly of DNA and RNA sequences, particularly where specific amino group protection is required.
• Prodrug Development: Serves as a protected precursor in the design of prodrugs to enhance the bioavailability and stability of active nucleoside ingredients.
• Biochemical Research: Employed in studies investigating nucleotide metabolism, enzyme mechanisms, and nucleic acid chemistry.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and the production of high-value, research-grade chemicals.

Basic Information

Product Name	N4,5'-o-Dibenzoyl-2'-Deoxycytidine
CAS No.	161664-22-8
Molecular Formula	C24H23N3O6
Molecular Weight	449.46 g/mol
Synonyms	2'-Deoxycytidine, N4,5'-bis(benzoyl)-; 5'-O-Benzoyl-N4-benzoyl-2'-deoxycytidine; N4,5'-Di-O-benzoyl-2'-deoxycytidine; 1-[(2R,4S,5R)-4-Benzoyloxy-5-(hydroxymethyl)oxolan-2-yl]-4-benzoylaminopyrimidin-2-one; 2'-Deoxycytidine N4,5'-dibenzoate; N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine; Protected 2'-Deoxycytidine Derivative
EINECS	Contact for details

Quality Control

Our N4,5'-o-Dibenzoyl-2'-Deoxycytidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' compliance needs in GMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.