Description

3-Thiophenecarboxamide, 5-β-D-Ribofuranosyl- is a specialized nucleoside analog that serves as a critical building block in advanced organic synthesis and pharmaceutical research. Its unique structure, featuring a thiophene ring fused with a ribofuranosyl sugar moiety, makes it a valuable precursor for developing novel antiviral and anticancer agents. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for complex synthetic pathways and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing nucleic acid metabolism pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and the design of novel bioactive molecules.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex heterocyclic compounds and labeled analogs for diagnostic applications.
• Academic Research: Utilized in universities and research institutes for studying carbohydrate chemistry and heterocycle modifications.

Basic Information

Product Name	3-Thiophenecarboxamide, 5-β-D-Ribofuranosyl-
CAS No.	161407-67-6
Molecular Formula	C10H13NO5S
Molecular Weight	259.28 g/mol
Synonyms	5-β-D-Ribofuranosyl-3-thiophenecarboxamide; 5-(β-D-Ribofuranosyl)thiophene-3-carboxamide; 3-Carbamoyl-5-(β-D-ribofuranosyl)thiophene; 5-(β-D-Ribofuranosyl)-3-thiophenecarboxamide; TSA (in specific research contexts); Thiophene nucleoside analog; 3-Thiophenecarboxamide, 5-β-D-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxamide, 5-β-D-Ribofuranosyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.