Description

Acetyl Arabinofuranosyl)-Adenine is a chemically modified nucleoside analog, specifically an adenine derivative with an arabinofuranosyl sugar moiety protected by an acetyl group. This compound is of significant value in pharmaceutical research and development, serving as a critical building block and intermediate for the synthesis of novel antiviral and anticancer agents. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of nucleoside-based therapeutics, diagnostic probes, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of antiviral drugs targeting viral polymerases.
• Anticancer Research: Used in the synthesis of nucleoside analogs studied for their potential to inhibit cancer cell proliferation.
• Biochemical Tool: Serves as a modified substrate in enzymatic studies to understand nucleoside metabolism and processing.
• Diagnostic Probe Development: Utilized in creating labeled nucleotides for molecular diagnostics and imaging applications.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Life Science Research: Applied in academic and industrial research exploring nucleic acid chemistry and biology.

Basic Information

Product Name	Acetyl Arabinofuranosyl)-Adenine
CAS No.	161109-77-9
Molecular Formula	C17H21N5O6
Molecular Weight	391.38 g/mol
Synonyms	9-[(2R,3S,4S,5R)-3,4-Diacetyloxy-5-(acetyloxymethyl)oxolan-2-yl]-9H-purin-6-amine; 2',3',5'-Tri-O-acetyl-β-D-arabinofuranosyladenine; 1-(2,3,5-Tri-O-acetyl-β-D-arabinofuranosyl)adenine; Ara-A Triacetate; β-D-Arabinofuranosyladenine 2',3',5'-triacetate; Adenine Arabinoside Triacetate; Vidarabine Triacetate
EINECS	Contact for details

Quality Control

Our Acetyl Arabinofuranosyl)-Adenine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.