Description

Cyclobutanecarbonyl Isothiocyanate (9Ci) is a specialized organic building block featuring a reactive isothiocyanate group attached to a cyclobutane carbonyl scaffold. This compound matters for its utility as a key intermediate in the synthesis of heterocyclic compounds and functionalized cyclobutane derivatives, enabling advanced research and development. It is primarily needed by pharmaceutical researchers, agrochemical developers, and academic chemists working on novel bioactive molecules and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those containing thiourea or heterocyclic motifs.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the reactivity of the isothiocyanate group.
• Chemical Synthesis: Acts as a versatile building block for constructing complex organic molecules, including ligands for catalysis.
• Material Science: Employed in the research of novel polymers or functional materials where the cyclobutane ring imparts specific structural properties.
• Bioconjugation & Probe Development: Useful for modifying biomolecules or creating fluorescent probes due to the isothiocyanate group's affinity for amines.

Basic Information

Product Name	Cyclobutanecarbonyl Isothiocyanate (9Ci)
CAS No.	161063-30-5
Molecular Formula	C6H7NOS
Molecular Weight	141.19 g/mol
Synonyms	Cyclobutanecarbonyl isothiocyanate; Cyclobutanecarboxylic acid isothiocyanate; 1-Cyclobutanecarbonyl isothiocyanate; Isothiocyanic acid cyclobutanecarbonyl ester; NSC 405124; Cyclobutanoyl isothiocyanate; Cyclobutylcarbonyl isothiocyanate
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Isothiocyanate (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.