Description

2-(1H-Imidazol-1-Yl)Acetyl Chloride is a highly reactive acyl chloride derivative, serving as a critical building block for the synthesis of complex organic molecules. Its core value lies in enabling the efficient introduction of the imidazole-acetyl moiety, a key functional group in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Building block for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Bioconjugation and Probe Synthesis: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.
• Polymer and Material Science: Monomer or modifier for creating polymers with specific imidazole-based functionalities.
• Custom Chemical Synthesis: Serves as a versatile reagent for contract research organizations (CROs) and fine chemical suppliers.

Basic Information

Product Name	2-(1H-Imidazol-1-Yl)Acetyl Chloride
CAS No.	160975-66-6
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	2-(1H-Imidazol-1-yl)acetyl chloride; 1H-Imidazole-1-acetyl chloride; (1H-Imidazol-1-yl)acetyl chloride; 2-(Imidazol-1-yl)acetyl chloride; Imidazole-1-acetyl chloride; 160975-66-6; 2-(1H-Imidazol-1-yl)ethanoyl chloride
EINECS	Contact for details

Quality Control

Our 2-(1H-Imidazol-1-Yl)Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.