Description

1H-Benzimidazole-5-Carbonylchloride(9Ci) is a high-purity organic building block and key synthetic intermediate. This compound is valued for its reactive carbonyl chloride group, which enables efficient amide bond formation and further functionalization of the benzimidazole core. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel benzimidazole-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and plant growth regulators that leverage the benzimidazole pharmacophore.
• Material Science: Serves as a monomer or cross-linking agent for creating advanced polymers with specific thermal or chemical resistance properties.
• Organic Synthesis: An essential building block for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Bioconjugation: Employed in the modification of biomolecules, such as peptides or proteins, for diagnostic and biochemical research applications.

Basic Information

Product Name	1H-Benzimidazole-5-Carbonylchloride(9Ci)
CAS No.	160882-30-4
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	1H-Benzimidazole-5-carbonyl chloride; 5-(Chlorocarbonyl)-1H-benzimidazole; 1H-Benzimidazole-5-carboxylic acid chloride; Benzimidazole-5-carbonyl chloride; 5-Carboxybenzimidazole chloride; 160882-30-4; 5-Benzimidazolecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-5-Carbonylchloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.