Description

D-Threo-Pentitol, 2,5-Anhydro-1,3,4-Trideoxy-2-C-(2,4-Difluorophenyl)-4-(Hydroxymethyl)-1-(1H-1,2,4-Triazol-1-Yl)- CAS NO 160709-02-4 is a high-purity, complex organic intermediate featuring a unique pentitol-derived scaffold modified with difluorophenyl and triazole moieties. This compound is of significant value for its role as a key building block in advanced pharmaceutical synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antifungal and antiviral agents, leveraging the biological activity of the triazole ring system.
• Agrochemical Research: Used in the development of new crop protection chemicals, where the difluorophenyl group can enhance bioavailability and stability.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Bioconjugation & Probe Development: The functional groups allow for further chemical modification, making it suitable for creating biochemical probes and labeled compounds.
• Academic & Institutional Research: Utilized in universities and research institutes for studying carbohydrate mimetics and enzyme inhibitors.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential commercial drug candidates.

Basic Information

Product Name	D-Threo-Pentitol, 2,5-Anhydro-1,3,4-Trideoxy-2-C-(2,4-Difluorophenyl)-4-(Hydroxymethyl)-1-(1H-1,2,4-Triazol-1-Yl)-
CAS No.	160709-02-4
Molecular Formula	C14H15F2N3O2
Molecular Weight	295.29 g/mol
Synonyms	2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; (2R,3S,4R)-2-(2,4-Difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)tetrahydrofuran-3-ol; Difluorophenyl Triazole Pentitol Derivative; CAS 160709-02-4; 1-(1H-1,2,4-Triazol-1-yl)-2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-D-threo-pentitol
EINECS	Contact for details

Quality Control

Our D-Threo-Pentitol, 2,5-Anhydro-1,3,4-Trideoxy-2-C-(2,4-Difluorophenyl)-4-(Hydroxymethyl)-1-(1H-1,2,4-Triazol-1-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.