Description

5'-Cytidylic Acid, 2'-Deoxy-5-Methyl-, Disodium Salt is a modified nucleoside monophosphate salt, a key building block in oligonucleotide synthesis. This high-purity intermediate is critical for research and development in advanced therapeutic areas, including antisense oligonucleotides and siRNA. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on nucleic acid-based drug discovery and development.

Application

• Oligonucleotide Synthesis: As a phosphoramidite precursor for the solid-phase synthesis of modified DNA strands.
• Antisense Therapy Development: Incorporation into oligonucleotides designed to target specific mRNA sequences for therapeutic intervention.
• siRNA and miRNA Research: Used in the manufacture of small interfering RNA (siRNA) and microRNA (miRNA) analogs for gene silencing studies.
• Diagnostic Probe Manufacturing: A component in the production of labeled probes for genetic testing and molecular diagnostics.
• Biochemical Research: Serving as a substrate or intermediate in enzymatic studies and metabolic pathway investigations.
• Pharmaceutical Intermediates: A high-value raw material in the cGMP production of novel nucleic acid therapeutics.

Basic Information

Product Name	5'-Cytidylic Acid, 2'-Deoxy-5-Methyl-, Disodium Salt
CAS No.	160509-70-6
Molecular Formula	C10H13N3Na2O7P
Molecular Weight	379.17 g/mol
Synonyms	5-Methyl-2'-deoxycytidine-5'-monophosphate disodium salt; 5-Methyl-dCMP disodium salt; 2'-Deoxy-5-methylcytidine 5'-monophosphate disodium salt; 5-Methyldeoxycytidylic acid disodium salt; d5mCMP disodium salt
EINECS	Contact for details

Quality Control

Our 5'-Cytidylic Acid, 2'-Deoxy-5-Methyl-, Disodium Salt is manufactured under strict quality systems suitable for pharmaceutical R&D. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS. We provide comprehensive Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.