Description

3-Cyclohexene-1-Carbonyl Chloride, 2-Methoxy-, (1S-Cis)- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its value lies in its reactive acid chloride functionality and defined stereochemistry, enabling the precise construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity and environmental selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of high-value, performance chemicals such as liquid crystals, flavors, and fragrances requiring specific stereochemical purity.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis, exploring new C-C and C-heteroatom bond-forming reactions.

Basic Information

Product Name	3-Cyclohexene-1-Carbonyl Chloride, 2-Methoxy-, (1S-Cis)- (9Ci)
CAS No.	159415-27-7
Molecular Formula	C9H11ClO2
Molecular Weight	186.63 g/mol
Synonyms	(1S,2S)-2-Methoxy-3-cyclohexene-1-carbonyl chloride; (1S-cis)-2-Methoxy-3-cyclohexene-1-carboxylic acid chloride; 2-Methoxy-δ³-cyclohexene-1-carbonyl chloride, (1S-cis)-; (1S,2S)-2-Methoxycyclohex-3-ene-1-carbonyl chloride; (-)-(1S,2S)-2-Methoxy-3-cyclohexene-1-carbonyl chloride; (1S,2S)-rel-2-Methoxy-3-cyclohexene-1-carbonyl chloride; 3-Cyclohexene-1-carbonyl chloride, 2-methoxy-, (1S-cis)-; 159415-27-7
EINECS	Contact for details

Quality Control

Our production of 3-Cyclohexene-1-Carbonyl Chloride, 2-Methoxy-, (1S-Cis)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.