Description

Diethyl 4-Oxobutylphosphonate is a versatile organophosphorus compound, specifically a phosphonate ester, that serves as a critical building block in organic synthesis. Its primary value lies in its bifunctional reactivity, featuring both a carbonyl group and a phosphonate moiety, making it an excellent precursor for the Horner-Wadsworth-Emmons (HWE) olefination reaction. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity intermediates for constructing complex molecules, such as α,β-unsaturated carbonyl compounds and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with olefinic linkages.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and plant growth regulators that require specific phosphonate-based structures.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Reagent: Employed in the Horner-Wadsworth-Emmons reaction as a stabilized ylide precursor for the efficient generation of alkenes.
• Flavor & Fragrance Industry: Utilized in the synthesis of specific aroma chemicals and flavoring agents.
• Ligand & Catalyst Development: Serves as a precursor for phosphine-based ligands used in transition metal catalysis.

Basic Information

Product Name	Diethyl 4-Oxobutylphosphonate
CAS No.	158957-14-3
Molecular Formula	C8H17O4P
Molecular Weight	208.19 g/mol
Synonyms	4-Oxobutylphosphonic Acid Diethyl Ester; Diethyl (4-Oxobutyl)phosphonate; Diethyl 4-Oxobutylphosphonate; Butyrylphosphonic Acid Diethyl Ester; 4-Ketobutylphosphonic Acid Diethyl Ester; (4-Oxobutyl)phosphonic Acid Diethyl Ester; Diethyl 4-Oxobutyl Phosphonate; 158957-14-3
EINECS	Contact for details

Quality Control

Our Diethyl 4-Oxobutylphosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.435 - 1.445
Density	1.10 - 1.20 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.